Epitalon

Pineal Peptide

Epitalon

Epitalon (Epithalon) is a synthetic tetrapeptide widely studied for its role in cellular senescence pathways, telomere-related signaling, and age-associated regulatory mechanisms.

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Certificate of Analysis
Tested for Identification, Purity, Mass, Endotoxins, Sterility, and Heavy Metals
LATEST 6× TESTED
99.72%
PURITY
Variant Epitalon 10MG
Lot # EPIT-2602-A01
Labeled 10mg
Actual 10.21mg
Tested April 1, 2026
Heavy Metals Within Limits
Endotoxins Pass
Sterility No Growth
Compound Information
Pharmaceutical Specifications
Molecular Profile
What Is Epitalon?
TypeSynthetic peptide
CAS Number307297-39-8
Molecular FormulaC₁₄H₂₂N₄O₉
Molecular Weight390.35 g/mol
Amino Acids4
PubChem Database
Storage Requirements
Stability Information
Freeze for storage Refrigerate after reconstitution Protect from light
Lyophilized (powder)
-20°C  ·  24+ months
Reconstituted
2-8°C  ·  ~30 days
Research
Sources & References
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (MDPI)
Overview of Epitalon — Highly Bioactive Pineal Tetrapeptide with Promising Properties
2025  ·  DOI: 10.3390/ijms26062691
Araj SK, Brzezik J, Mądra-Gackowska K, Szeleszczuk Ł
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BIOGERONTOLOGY (SPRINGER)
Epitalon Increases Telomere Length in Human Cell Lines Through Telomerase Upregulation or ALT Activity
2025  ·  DOI: 10.1007/s10522-025-10315-x
Al-dulaimi S, Thomas R, Matta S, Roberts T
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MOLECULES (MDPI)
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
2020  ·  DOI: 10.3390/molecules25030609
Khavinson V, Diomede F, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S, Sinjari B
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (MDPI)
Neuroepigenetic Mechanisms of Action of Ultrashort Peptides in Alzheimer's Disease
2022  ·  DOI: 10.3390/ijms23084259
Khavinson V, Linkova N, Petukhov M, et al.
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JOURNAL OF INTEGRATIVE MEDICINE (ELSEVIER)
Improving Biological Age, Telomere Length, and Cognition: A Case Report on the Use of Therapeutic Plasma Exchange, Peptides, Umbilical Cord Tissue MSCs and Exosomes
2024  ·  DOI: 10.14200/jrm.2024.0012
Gaines DW, et al.
View Source
BIOGERONTOLOGY (SPRINGER)
Peptide Bioregulation of Aging: Results and Prospects
2010  ·  DOI: 10.1007/s10522-009-9249-8
Anisimov VN, Khavinson VK
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BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (SPRINGER)
Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells
2003  ·  DOI: 10.1023/A:1025493705728
Khavinson VK, Bondarev IE, Butyugov AA
View Source
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (SPRINGER)
Effect of Pineal Tetrapeptide on Antioxidant Defense in Drosophila melanogaster
2000  ·  DOI: 10.1007/BF02439268
Khavinson VK, et al.
View Source
Epitalon $29.99

Pineal Peptide

Epitalon (Epithalon) is a synthetic tetrapeptide widely studied for its role in cellular senescence pathways, telomere-related signaling, and age-associated regulatory mechanisms.

Additional information

Dosage:

10MG

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